This medication could consist of sugar and/or Alcoholic beverages. Warning is suggested When you've got diabetic issues, alcohol dependence, or liver disorder. Ask your physician or pharmacist about utilizing this merchandise properly.
Observational studies have shown that concomitant utilization of opioid analgesics and benzodiazepines enhances the hazard of drug-connected mortality as compared to utilization of opioids on your own.
Notify your health practitioner If you're pregnant or Feel you may be pregnant. For the duration of pregnancy, this merchandise isn't encouraged. It may damage an unborn child. Talk to your medical professional in regards to the dangers and advantages of this medication. See also Warning section.
Signals and indications of overdosage with promethazine HCl range between moderate despair of the central anxious method and cardiovascular program to profound hypotension, respiratory depression, unconsciousness, and sudden Loss of life.
For example, quite a few reported cases of Dying occurred inside the put up-operative period following tonsillectomy and/or adenoidectomy, and plenty of of the children had evidence of being ultra-fast metabolizers of codeine. Also, little ones with obstructive rest apnea who are dealt with with codeine for write-up-tonsillectomy and/or adenoidectomy ache may very well be especially delicate to its respiratory depressant result. As a result of hazard of lifetime-threatening respiratory melancholy and Demise:
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When you are prescribed this medication on an everyday routine and overlook a dose, get it the moment you don't forget. If it is near the time of another dose, skip the missed dose. Just take your next dose with the frequent time. Never double the dose to catch up.
When the response to an opioid antagonist is suboptimal or only transient in mother nature, administer supplemental antagonist as directed because of the merchandise’s prescribing info. The respiratory depressant effects of promethazine aren't reversed by opioid antagonists, for example naloxone.
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Promethazine HCl and Codeine Phosphate Oral Solution exposes patients as well as other end users to the challenges of opioid addiction, abuse, and misuse, which may result in overdose and death. Reserve Promethazine HCl and Codeine Phosphate Oral Alternative for use in adult patients for whom the main advantages of cough suppression are anticipated to outweigh the threats, and in whom an ample evaluation of your etiology with the cough has been manufactured.
Take this medication just as prescribed to reduce the chance of habit. Ask your physician or pharmacist For additional facts.
Breathing challenges (respiratory melancholy)that may result in death and opioid withdrawal can take place if you start getting or end Promethazine codeine syrup having other medicines while getting Promethazine Hydrochloride and Codeine Phosphate Oral Alternative, including:
Opioid analgesics and antitussives, which include codeine, on the list of active components in Promethazine HCl and Codeine Phosphate Oral Answer, really should not be Employed in people with acute febrile sickness connected with productive cough or in patients with Continual respiratory disease exactly where interference with power to very clear the tracheobronchial tree of secretions would have a deleterious effect on the client’s respiratory perform.
Concomitant administration of promethazine products with other respiratory depressants has an association with respiratory despair, and in some cases Dying, in pediatric clients.